This workshop gathers in an open and interactive forum, the Principal Investigators of the Theoretical Neuroscience “pillar” (SP4) of the Human Brain Project. SP4 provides novel mathematical descriptions for multi-scale representations of the brain and its components, from cellular to network levels. We propose to focus this workshop on how microscopic processes in the brain express themselves parametrically on a higher level of organisation, ranging from populations of neurons, entire brain areas to the whole-brain networks. Individual talks will address and discuss the following research questions:

• How can mean-field models achieve a direct faithful integration between mesoscopic and macroscopic signals (e.g. LFP, EEG, fMRI)?
• How can building blocks, including different signals of the brain, be incorporated into simplified descriptions of dendrites, generic models, and synaptic plasticity?
• What is the state-of-the art of large-scale models of the whole brain?
• Which do recent advances in modelling synaptic plasticity and memory tell about computational properties of the neocortex?
• How close is our community to the modelling of the whole-brain?

Speakers:

• Andrej Bicanski, University College London
• Neil Burgess, University College London
• Marc De Kamps, University of Leeds
• Alain Destexhe, EITN CNRS UNIC
• Gaute Einevoll, NMBU
• Olivier Faugeras, INRIA
• Michele Giugliano, University of Antwerpen
• Sonja Grün, FZ Juelich
• Moritz Helias, FZ Juelich
• Viktor Jirsa, Aix Marseille University
• Marja-Leena Linne,Tampère University of Technology
• Sacha van Albada, FZ Juelich
• Gorka Zamora-López, UPF